ProCipitate - Protein removal/DNA enrichment & isolation reagent, substitute to phenol/chloroform (100 mL)

Description

ProCipitate is a unique protein removal reagent based upon patented elastomeric polyelectrolytes. The polymer chains of ProCipitate are initially extended in a high energy state due to an overall net negative charge. When introduced to protein solutions, the charges are neutralized and the polymer chains collapse to a more favorable energy state; DNA and RNA remain unreacted and stay in solution. ProCipitate is non-hazardous and can replace phenol/chloroform with the additional benefits of solid-phase suspensions: adaptability to filtration and automation. It is routinely used for plasmids, cosmids, BACs, and genomic DNA, as well as RNA. ProCipitate can also be used to remove Proteinase K and other enzymes. ProCipitate provides high quality DNA suitable for automated sequencing, southern blotting, and restriction digestion. ProCipitate is supplied as a suspension reagent and in ProPrep kits for specific application formats. For Research Use Only