Product Profile

Although ethanol (alcohol) in small amounts can increase HDL, or “good” cholesterol, the primary heart-protective effect of wine comes from pigments in the skin of dark grapes. Red wine is particularly rich in such pigments, which are liberated during fermentation. The most scientifically supported and celebrated of the compounds is resveratrol (3,4,5-trihydroxystilbene). The compound evolved in grapes to combat disease, especially fungal attack. As evidence, treatment with fungicides dramatically reduces resveratrol production by the grape. Processing to reduce the astringent tannin content of wines, as performed commercially at large vintners, can also unfortunately reduce wine’s protective effect. Populations that regularly consume red wine are noted for longevity and general good health. Indeed, red wine consumption and superior health is prevalent in much of Mediterranean Europe. This health- promoting effect may help explain part of the “French Paradox:” the French have been observed to consume large amounts of saturated fats and yet exhibit low rates of heart disease. Along with resveratrol, red wine also contains quercetin, catechins, anthocyanins, and proanthocyanins. Therefore, the synergy found in Jarrow Formulas Resveratrol Synergy is a natural one. Jarrow Formulas uses especially rich sources of resveratrol, catechins, anthocyanins, and proanthocyanins, along with quercetin, to create a concentrated supplement that promotes the cardiovascular protection found with red wine, without the alcohol.* The resveratrol used has been extracted from the root of the Chinese herb Huzhang (Polygonum cuspidatum), the catechins from green tea extract, the anthocyanins from grape skin extract, and the proanthocyanins from grape seed extract. Quercetin is also added to support the antioxidant and cardiovascular health promoting effects of these other wine components.*

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Distinguishing Features:

20 mg resveratrols per tablet
Easy-solv tablets
Synergistic formula
Includes stilbenes, catechins, anthocyanins, & OPCs

What Does Resveratrol Do?

Classified biologically as a phytoalexin and chemically as a stilbene, resveratrol has been investigated in clinical studies in a number of areas, including life extension, healthy cell replication, blood-sugar support, and cardiovascular health.* Resveratrol also displays a neutralizing effect on environmental toxins. Environmental contaminants such as dioxin, found at high levels in cigarette smoke and in many other sources of air pollution, have been linked to various health problems. The mechanistic details concerning how this occurs are not completely understood, but resveratrol may stimulate human defense systems in a similar way as it does in grapes.* In fact, research suggests that resveratrol activates phase II detoxification systems in humans.*

Cardiovascular Protection*

The cardioprotective effect of wine is normally attributed to its antioxidants. Investigations have shown that all of these red wine polyphenolic antioxidants including resveratrol, catechins, anthocyanins, and proanthocyanins play a role in cardioprotection.* Many scientists have studied the mechanisms by which polyphenolic compounds protect the cardiovascular system. Such protection is attributed in part to their ability to directly scavenge peroxyl and hydroxyl radicals and to reduce oxidative stress.* These actions, among other things, protect LDL (“bad” cholesterol) from oxidation, helping to promote cardiovascular health.* Since these compounds work by different mechanisms, they may work best in combination. Resveratrol was proven more effective than flavonoids in chelating copper ions – generators of free radicals.* Overall resveratrol supports cardiovascular function by inhibiting LDL oxidation, upregulating nitric oxide synthesis, and supporting the integrity of capillaries.* Anthocyanins and proanthocyanins (also known as “tannins”) may also have positive effects on inflammation health.*

Synergistic Supporting Cast

One primary benefit of resveratrol and proanthocyanins is in protecting vitamin C against premature oxidation, especially by metal ions. Therefore, vitamin C has been added along with its protectors. Broader protection comes from green tea catechins, grape skin anthocyanins, grape seed OPC (Oligomeric ProanthoCyanidins), pterostilbene, and quercetin. Now, five of the best-researched wine antioxidants and health components are together with vitamin C in one supplement–Resveratrol Synergy.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Weight	0.2 Kilograms
Brand	Jarrow Formulas
Format	Tablet

Jarrow Formulas Resveratrol Synergy, 60 Tablets

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