Description
- <br>Host: Rabbit<br/> <br>Antigen (Uniprot Accession, Gene or protein): Melanocyte protein PMEL <br/> <br>Conjugate: HRP<br/> <br>Clonality: Polyclonal<br/> <br>Clone: N/A<br/> <br>Species: Human<br/> <br>Applications: ELISA<br/> <br>Isotype: IgG<br/> <br>Citation: N/A<br/> <br>Shipping Temp: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.<br/>
- <br>Uniprot ID: P40967<br/> <br>Gene: PMEL<br/> <br>Storage buffer correct: 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4<br/> <br>Purity: Caprylic Acid Ammonium Sulfate Precipitation Purified<br/> <br>Alternative Names: ME20-M, Short name=ME20M, Melanocyte protein Pmel 17, Melanocytes lineage-specific antigen GP100, Melanoma-associated ME20 antigen, P1, P100, Premelanosome protein, Silver locus protein homolog, D12S53E, PMEL17, SILV , PMEL<br/>
- <br>Product Size: 100 µg<br/>
Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.