---
product_id: 5935185
title: "NOW Foods Supplements, SAMe (S-Adenosyl-L-Methionine) 400 mg, Nervous System Support*, 60 Tablets"
brand: "now foods"
price: "A$91"
currency: AUD
in_stock: true
reviews_count: 8
category: "Now Foods"
url: https://www.desertcart.com.au/products/5935185-now-foods-supplements-same-s-adenosyl-l-methionine-400-mg
store_origin: AU
region: Australia
---

# gluten, dairy, soy & sugar free 400 mg potent SAMe dose crosses blood-brain barrier NOW Foods Supplements, SAMe (S-Adenosyl-L-Methionine) 400 mg, Nervous System Support*, 60 Tablets

**Brand:** now foods
**Price:** A$91
**Availability:** ✅ In Stock

## Summary

> 💡 Elevate your mind & joints with clinically proven SAMe — because feeling your best is non-negotiable.

## Quick Answers

- **What is this?** NOW Foods Supplements, SAMe (S-Adenosyl-L-Methionine) 400 mg, Nervous System Support*, 60 Tablets by now foods
- **How much does it cost?** A$91 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.com.au](https://www.desertcart.com.au/products/5935185-now-foods-supplements-same-s-adenosyl-l-methionine-400-mg)

## Best For

- now foods enthusiasts

## Why This Product

- Trusted now foods brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Sustainable Wellness Investment:** Subscribe & save option makes premium brain and joint support affordable long-term.
- • **Clean, Trusted Quality Assurance:** GMP-certified, allergen-free formula from a family-owned USA brand since 1968.
- • **Convenient, Easy-to-Swallow Tablet:** Smaller oval tablets with no enteric coating needed for hassle-free daily use.
- • **Clinically Supported Brain & Mood Boost:** Backed by Harvard studies, SAMe doubles antidepressant response rates with fewer side effects.
- • **Triple-Action Nervous System & Joint Support:** Targets neurotransmitter synthesis, joint comfort, and emotional well-being simultaneously.

## Overview

NOW Foods SAMe 400 mg delivers a potent, clinically validated dose of S-adenosylmethionine in a clean, allergen-free tablet designed to support brain chemistry, mood balance, and joint health. Manufactured under strict GMP standards in the USA, this trusted supplement crosses the blood-brain barrier to enhance neurotransmitter synthesis and promote emotional well-being, making it a top choice for professionals seeking natural, effective nervous system support.

## Description

Product Description Stabilized SAMe, Smaller Tablet No Enteric Coating Needed Supports Joint Health* SAMe (S-adenosylmethionine), a compound native to the body, is a component of many biochemical reactions, including those that affect brain biochemistry and joint health.* Numerous studies have indicated that SAMe can help to alleviate transient minor aches and pains resulting from overexertion or strain.* In addition, because SAMe is also necessary for the synthesis of neurotransmitters, it plays an important role in mood support.* Natural color variation may occur in this product. Brand Story By

Review: Much better for you than other options - I started taking these after I was told that these are better than most pharmaceutical drugs. I would much rather take herbal remedies than any other pharmaceutical drugs any day. I put some information on here for others to see just how great SAMe is for you. New Human Study Confirms Potent Antidepressant Effects of SAMe December 2010 By David Hoffnung Life Extension® introduced SAMe (S-adenosylmethinone) in 1997. Back then it was enormously popular in Europe, but unknown in the United States. The National Institute of Mental Health decided to fund a double-blind, placebo-controlled trial that would evaluate SAMe as an additive therapy in those suffering major depression who were resistant to FDA-approved drugs. Researchers at Harvard Medical School and Massachusetts General Hospital gave patients 800 mg of SAMe twice daily along with a selective serotonin reuptake inhibiting drug (SSRI). Relative to placebo, patients who received the SAMe showed a 105% higher response rate and a 121% higher remission rate.1 Said differently, add-on therapy with SAMe in patients with drug-resistant depression produced double the response rate AND remission rate compared with placebo within a 6-week period. This study was published in the August 2010 issue of the American Journal of Psychiatry.1 It was a follow-up to a 2004 pilot study that showed greater benefits when antidepressant drugs were combined with SAMe than when the same drugs were taken alone.2 For the past 13 years, SAMe has been on Life Extension’s TOP TEN list of the most important steps to take to ensure optimal longevity. SAMe has been recommended to aging individuals not to just feel better, but also to protect the brain, liver, joints, and other tissues of the body like no other substance. This article reviews and updates the many studies documenting the anti-aging properties of SAMe. A listing of all the drugs the FDA has approved to treat depression would fill several pages of this magazine. A major problem with these antidepressant drugs is that they fail a significant number of patients—up to 30%, by some accounts.3 In many cases, the drugs make depressed individuals feel worse, and FDA-mandated labeling now requires a warning that use of some antidepressants increases suicide risk—which is an incredible contradiction considering that suicide is a leading cause of death amongst depressives. An equally disconcerting issue is the many side effects associated with antidepressant medications such as weight gain, constipation, dry mouth, and other symptoms that cause many depressives to stop using them. There is thus an urgent need for a new approach to treating those who fail to respond to currently available antidepressant medications. Encouraging news from a recent study shows that the addition of S-adenosylmethinone (SAMe) to a serotonin reuptake inhibitor drug markedly improves the percentage of severe depressives who are relieved of their disorder. Unlike synthetic prescription drugs that induce unintended side effects, SAMe is a naturally-occurring agent in the body that performs a multitude of beneficial functions, such as boosting glutathione levels in the brain and liver. The anti-aging properties of SAMe are so profound that non-depressives take it each day (in lower doses) just like they do their other dietary supplements.4,5 Antidepressants Don’t Work As a team of Harvard researchers noted in a remarkable 2010 study published in the Journal of Clinical Psychiatry,6 “The majority of depressed patients will not experience remission when treated with a first-line antidepressant.” In other words, antidepressants don’t really work for most patients. More is needed to help depression’s victims. This is where SAMe comes in. In modern high-tech imaging studies of healthy human brains, SAMe produces effects typical of several classes of antidepressant drugs7—but unlike those drugs, SAMe has remarkably few side effects and is well-tolerated even in elderly subjects.8 People with depression may exhibit a variety of biochemical imbalances, but the most common and best-known has to do with neurotransmitters like serotonin (involved in mood, sleep, appetite, and learning) and norepinephrine (involved in heart rate, blood pressure, and the fight-or-flight response). These chemical messengers belong to a class of molecules known as monoamines, and their synthesis in brain cells is largely controlled by the presence of folic acid, vitamin B12—and SAMe.9-12 When released into the space between brain cells (the synapse), monoamines exert stimulating or inhibiting effects on postsynaptic neurons. With too little serotonin or norepinephrine available, the brain cannot sustain a positive mood—and depression results. Virtually all antidepressant drugs work to boost levels of these neurotransmitters within the synapse. And therein lie many of their limitations—and the causes of many of their side effects.13 SAMe operates through a completely different mechanism than these drugs. A molecule derived from the sulfur-containing amino acid methionine, SAMe is found in every living cell and plays a central role in cellular function.14,15 In addition to being required for monoamine synthesis, it also affects cell membrane fluidity, which may in turn influence how well a neuron transmits an electrical signal.16 Recent studies have shown that SAMe is also involved in the so-called “epigenetic” control of cellular function—the ability of cells to activate or suppress specific genes based on environmental influences—by its effects on proteins associated with chromosomes.17 These multi-targeted effects, coupled with an extraordinary safety profile, make SAMe a compelling treatment for a wide variety of brain disorders, from depression and cognitive decline to congenital metabolic dysfunction.18,19 SAMe crosses the blood-brain barrier, making it readily available to the brain and nervous system.10 This is vital: SAMe levels in the spinal fluid of depressed individuals have been shown to be significantly lower than those of healthy people.11 Animal models of depression shed additional light on how SAMe works in the brain. More than two decades ago Japanese scientists demonstrated a reduction in aggression in rats treated with SAMe as a result of its action in the central nervous system.20 By the turn of this century, researchers in Italy and Spain showed that SAMe reverses experimentally-induced depression in rats, at a rate faster than that of the prescription antidepressant imipramine, the first tricyclic antidepressant developed, and without apparent side effects.21,22 And in a remarkably detailed study, the Italian group showed that SAMe restored diminished brain levels of “polyamines,” essential brain molecules that are reduced in depressed patients.23 In 2007 a team of scientists at the University of Massachusetts launched a study using a combination of SAMe with N-acetyl cysteine (NAC) and acetyl-L-carnitine.24 Their subjects were aging mice with neurodegeneration similar to Alzheimer’s disease, in which depression is often a major manifestation. The combination rapidly enhanced cognitive function and prevented or reduced aggression in the animals, an effect that was rapidly reversed when the combination was withdrawn. The combination also prevented a decline in levels of the neurotransmitter acetylcholine, while contributing important antioxidant effects as well. WHAT YOU NEED TO KNOW: SAME • A landmark study funded by the National Institute of Mental Health revealed that the addition of S-adenosylmethionine or SAMe produces compelling results in people taking SSRIs, the majority of whom do not experience relief when taking the drug alone. • SAMe is a naturally occurring molecule found in all living cells; it supports a host of chemical functions necessary for normal brain activity. • SAMe acts by several distinct and independent mechanisms to target multiple sites of action in brain cells that are involved in producing depression. • In clinical trials, SAMe has been shown to be at least as effective as prescription antidepressants, but with far fewer side effects. • Because of its strong safety record, SAMe should be part of any regimen for brain health, particularly when depressive symptoms are present—and when prescription drugs alone don’t work. • SAMe has also been shown to confer enormous benefits to the brain, liver, and joints, halting and even reversing various degenerative conditions, from osteoarthritis and neurodegeneration to nonalcoholic fatty liver disease. http://www.lifeextension.com/magazine/2010/12/new-human-study-confirms-potent-antidepressant-effects-of-same/page-01
Review: I take this vitamin daily, and am so thankful for it. - My doctor recommended I start taking Sam-e once I was diagnosed with fibromyalgia. It took a bit of trial and error to figure out my correct dosage (800 mg daily) , but now that I have I have been taking it consistently for about three years, it really has made a big difference in my life. I can tell when I haven't been taking it, especially if its a few days in a row, or even within the same week or two. It really helps my body to function, in a way that is easy to forget is attributed to this vitamin until I miss a few days. On days when I am taking in regularly it helps me to keep my thoughts together and focus a little more easily. It helps my body to feel like it has a little more energy and may even be able to recover from things a little better than it can without. This is not to say its a miracle vitamin, I still struggle with my issues daily, but it does offer a kind of understated support for my body that I am very thankful for. And for me, because it is not a gel cap, but one hard solid pill, it is easer to take. And I really like Now Foods (or Now Vitamins) as a company. I know that they test their products regularly, and use clean ingredients and that I can trust them. Its nice to not have to worry about buying a new supplement from them in that way because I know it will be safe. Especially if it is something I am going to be taking daily for probably the rest of my life, like this. One thing that is a little frustrating is that it is kind of expensive. But, it does come in a glass bottle, and I am taking kind of a high dose in comparison to what they offer (they offer a 200 mg vitamin as well which is much smaller both in size itself and in packaging.) And I do appreciate that they offer it as a subscribe and save option, which does make it more affordable in monthly increments.

## Features

- OVAL TABLET!: SAMe (S-adenosylmethionine), a compound native to the body, is a component of many biochemical reactions, including those that affect brain biochemistry and joint health*
- SUPPORTS NERVOUS SYSTEM, EMOTIONAL WELL-BEING, AND JOINT HEALTH*: Numerous studies have indicated that SAMe can help to alleviate transient minor aches and pains resulting from overexertion or strain.*
- CERTIFICATIONS/CLASSIFICATIONS: Dairy Free, Egg Free, Made without Gluten, Soy Free, Sugar Free
- GMP Quality Assured: A-rated, third-party certification means that every aspect of the NOW manufacturing process has been examined. Our in-house laboratories are ISO/IEC accredited for laboratory testing including for stability, potency and product formulation.
- Packaged in the USA by a family owned and operated company since 1968

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B000OSSQFY |
| Age Range Description | Adult |
| Allergen Information | Dairy Free, Egg Free, Soy Free |
| Best Sellers Rank | #30,270 in Health & Household ( See Top 100 in Health & Household ) #1,047 in Blended Vitamin & Mineral Supplements #2,225 in Sales & Deals |
| Brand | NOW Foods |
| Brand Name | NOW Foods |
| Color | Off White |
| Container Type | Bottle |
| Customer Reviews | 4.5 out of 5 stars 750 Reviews |
| Diet Type | Gluten Free |
| Dosage Form | Tablet,Tablets |
| Flavor | Unflavored |
| Global Trade Identification Number | 00733739001412 |
| Item Dimensions | 2.13 x 2.13 x 4 inches |
| Item Form | Tablet |
| Item Height | 4 inches |
| Item Weight | 3.2 ounces |
| Manufacturer | NOW Sports - Nutrition and Wellness |
| Material Features | Vegetarian |
| Model Name | SAMe 400 mg |
| Number of Items | 1 |
| Primary Supplement Type | multivitamin |
| Product Benefits | Bone & Joint Support |
| Total Servings Per Container | 60 |
| UPC | 733739001412 |
| Unit Count | 60 Count |

## Product Details

- **Age Range (Description):** Adult
- **Brand:** NOW Foods
- **Diet Type:** Gluten Free
- **Flavor:** Unflavored
- **Item Form:** Tablet
- **Item Weight:** 0.2 Pounds
- **Item dimensions L x W x H:** 2.13 x 2.13 x 4 inches
- **Primary Supplement Type:** multivitamin
- **Product Benefits:** Bone & Joint Support
- **Unit Count:** 60 Count

## Images

![NOW Foods Supplements, SAMe (S-Adenosyl-L-Methionine) 400 mg, Nervous System Support*, 60 Tablets - Image 1](https://m.media-amazon.com/images/I/71LzRoy+mKL.jpg)

## Available Options

This product comes in different **Size** options.

## Questions & Answers

**Q: I thought Sam-E needed to be in blister packs to preserve the pills themselves. I notice these are not. Is there a reason why?**
A: The blister pack is one issue - I notice they recommend refrigerating these after opening which would help preserve.The more important point to me is that these have no mannitol (stomach upsetting) in themand that they are a true 400mg dose of SAM-e- not 400mg of the salt compound as many others are.

**Q: What size are these pills? I have a hard time swallowing pills.**
A: Long flat tablets, 7/8” X 3/8”, smooth coating, I find them easy to swallow.  Don’t break them, they are enteric coated.  Exposure to your stomach acids will significantly impact their effectiveness.

**Q: Can these be cut?**
A: No they cannot. They are not supposed to dissolve in your stomach which is why they are to be taken on an empty stomach to have any effect. If you cut them, it affects the coating on the pill. They do come in different doses however so hopefully you can find one that suits your needs.

**Q: Where where they made? good practices facility does not mean anything to me. they packed them in usa but where were they made? what country?**
A: At NOW, our products are manufactured in the U.S. In regards to sourcing, our raw material sourcing is subject to change, so please contact us directly for information like country of origin. Anything we post here will later be inaccurate whenever we do make a change, so we are hesitant to post temporarily accurate information in a permanently accessible public forum. Our certified nutritionists can be reached at 888-669-3663 ext. 5 or productinfo@nowfoods.com.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Much better for you than other options
*by A***N on January 23, 2016*

I started taking these after I was told that these are better than most pharmaceutical drugs. I would much rather take herbal remedies than any other pharmaceutical drugs any day. I put some information on here for others to see just how great SAMe is for you. New Human Study Confirms Potent Antidepressant Effects of SAMe December 2010 By David Hoffnung Life Extension® introduced SAMe (S-adenosylmethinone) in 1997. Back then it was enormously popular in Europe, but unknown in the United States. The National Institute of Mental Health decided to fund a double-blind, placebo-controlled trial that would evaluate SAMe as an additive therapy in those suffering major depression who were resistant to FDA-approved drugs. Researchers at Harvard Medical School and Massachusetts General Hospital gave patients 800 mg of SAMe twice daily along with a selective serotonin reuptake inhibiting drug (SSRI). Relative to placebo, patients who received the SAMe showed a 105% higher response rate and a 121% higher remission rate.1 Said differently, add-on therapy with SAMe in patients with drug-resistant depression produced double the response rate AND remission rate compared with placebo within a 6-week period. This study was published in the August 2010 issue of the American Journal of Psychiatry.1 It was a follow-up to a 2004 pilot study that showed greater benefits when antidepressant drugs were combined with SAMe than when the same drugs were taken alone.2 For the past 13 years, SAMe has been on Life Extension’s TOP TEN list of the most important steps to take to ensure optimal longevity. SAMe has been recommended to aging individuals not to just feel better, but also to protect the brain, liver, joints, and other tissues of the body like no other substance. This article reviews and updates the many studies documenting the anti-aging properties of SAMe. A listing of all the drugs the FDA has approved to treat depression would fill several pages of this magazine. A major problem with these antidepressant drugs is that they fail a significant number of patients—up to 30%, by some accounts.3 In many cases, the drugs make depressed individuals feel worse, and FDA-mandated labeling now requires a warning that use of some antidepressants increases suicide risk—which is an incredible contradiction considering that suicide is a leading cause of death amongst depressives. An equally disconcerting issue is the many side effects associated with antidepressant medications such as weight gain, constipation, dry mouth, and other symptoms that cause many depressives to stop using them. There is thus an urgent need for a new approach to treating those who fail to respond to currently available antidepressant medications. Encouraging news from a recent study shows that the addition of S-adenosylmethinone (SAMe) to a serotonin reuptake inhibitor drug markedly improves the percentage of severe depressives who are relieved of their disorder. Unlike synthetic prescription drugs that induce unintended side effects, SAMe is a naturally-occurring agent in the body that performs a multitude of beneficial functions, such as boosting glutathione levels in the brain and liver. The anti-aging properties of SAMe are so profound that non-depressives take it each day (in lower doses) just like they do their other dietary supplements.4,5 Antidepressants Don’t Work As a team of Harvard researchers noted in a remarkable 2010 study published in the Journal of Clinical Psychiatry,6 “The majority of depressed patients will not experience remission when treated with a first-line antidepressant.” In other words, antidepressants don’t really work for most patients. More is needed to help depression’s victims. This is where SAMe comes in. In modern high-tech imaging studies of healthy human brains, SAMe produces effects typical of several classes of antidepressant drugs7—but unlike those drugs, SAMe has remarkably few side effects and is well-tolerated even in elderly subjects.8 People with depression may exhibit a variety of biochemical imbalances, but the most common and best-known has to do with neurotransmitters like serotonin (involved in mood, sleep, appetite, and learning) and norepinephrine (involved in heart rate, blood pressure, and the fight-or-flight response). These chemical messengers belong to a class of molecules known as monoamines, and their synthesis in brain cells is largely controlled by the presence of folic acid, vitamin B12—and SAMe.9-12 When released into the space between brain cells (the synapse), monoamines exert stimulating or inhibiting effects on postsynaptic neurons. With too little serotonin or norepinephrine available, the brain cannot sustain a positive mood—and depression results. Virtually all antidepressant drugs work to boost levels of these neurotransmitters within the synapse. And therein lie many of their limitations—and the causes of many of their side effects.13 SAMe operates through a completely different mechanism than these drugs. A molecule derived from the sulfur-containing amino acid methionine, SAMe is found in every living cell and plays a central role in cellular function.14,15 In addition to being required for monoamine synthesis, it also affects cell membrane fluidity, which may in turn influence how well a neuron transmits an electrical signal.16 Recent studies have shown that SAMe is also involved in the so-called “epigenetic” control of cellular function—the ability of cells to activate or suppress specific genes based on environmental influences—by its effects on proteins associated with chromosomes.17 These multi-targeted effects, coupled with an extraordinary safety profile, make SAMe a compelling treatment for a wide variety of brain disorders, from depression and cognitive decline to congenital metabolic dysfunction.18,19 SAMe crosses the blood-brain barrier, making it readily available to the brain and nervous system.10 This is vital: SAMe levels in the spinal fluid of depressed individuals have been shown to be significantly lower than those of healthy people.11 Animal models of depression shed additional light on how SAMe works in the brain. More than two decades ago Japanese scientists demonstrated a reduction in aggression in rats treated with SAMe as a result of its action in the central nervous system.20 By the turn of this century, researchers in Italy and Spain showed that SAMe reverses experimentally-induced depression in rats, at a rate faster than that of the prescription antidepressant imipramine, the first tricyclic antidepressant developed, and without apparent side effects.21,22 And in a remarkably detailed study, the Italian group showed that SAMe restored diminished brain levels of “polyamines,” essential brain molecules that are reduced in depressed patients.23 In 2007 a team of scientists at the University of Massachusetts launched a study using a combination of SAMe with N-acetyl cysteine (NAC) and acetyl-L-carnitine.24 Their subjects were aging mice with neurodegeneration similar to Alzheimer’s disease, in which depression is often a major manifestation. The combination rapidly enhanced cognitive function and prevented or reduced aggression in the animals, an effect that was rapidly reversed when the combination was withdrawn. The combination also prevented a decline in levels of the neurotransmitter acetylcholine, while contributing important antioxidant effects as well. WHAT YOU NEED TO KNOW: SAME • A landmark study funded by the National Institute of Mental Health revealed that the addition of S-adenosylmethionine or SAMe produces compelling results in people taking SSRIs, the majority of whom do not experience relief when taking the drug alone. • SAMe is a naturally occurring molecule found in all living cells; it supports a host of chemical functions necessary for normal brain activity. • SAMe acts by several distinct and independent mechanisms to target multiple sites of action in brain cells that are involved in producing depression. • In clinical trials, SAMe has been shown to be at least as effective as prescription antidepressants, but with far fewer side effects. • Because of its strong safety record, SAMe should be part of any regimen for brain health, particularly when depressive symptoms are present—and when prescription drugs alone don’t work. • SAMe has also been shown to confer enormous benefits to the brain, liver, and joints, halting and even reversing various degenerative conditions, from osteoarthritis and neurodegeneration to nonalcoholic fatty liver disease. http://www.lifeextension.com/magazine/2010/12/new-human-study-confirms-potent-antidepressant-effects-of-same/page-01

### ⭐⭐⭐⭐⭐ I take this vitamin daily, and am so thankful for it.
*by S***M on April 1, 2017*

My doctor recommended I start taking Sam-e once I was diagnosed with fibromyalgia. It took a bit of trial and error to figure out my correct dosage (800 mg daily) , but now that I have I have been taking it consistently for about three years, it really has made a big difference in my life. I can tell when I haven't been taking it, especially if its a few days in a row, or even within the same week or two. It really helps my body to function, in a way that is easy to forget is attributed to this vitamin until I miss a few days. On days when I am taking in regularly it helps me to keep my thoughts together and focus a little more easily. It helps my body to feel like it has a little more energy and may even be able to recover from things a little better than it can without. This is not to say its a miracle vitamin, I still struggle with my issues daily, but it does offer a kind of understated support for my body that I am very thankful for. And for me, because it is not a gel cap, but one hard solid pill, it is easer to take. And I really like Now Foods (or Now Vitamins) as a company. I know that they test their products regularly, and use clean ingredients and that I can trust them. Its nice to not have to worry about buying a new supplement from them in that way because I know it will be safe. Especially if it is something I am going to be taking daily for probably the rest of my life, like this. One thing that is a little frustrating is that it is kind of expensive. But, it does come in a glass bottle, and I am taking kind of a high dose in comparison to what they offer (they offer a 200 mg vitamin as well which is much smaller both in size itself and in packaging.) And I do appreciate that they offer it as a subscribe and save option, which does make it more affordable in monthly increments.

### ⭐⭐⭐⭐⭐ Helps with joint pain!
*by C***E on November 18, 2025*

Helps immensely with joint pain! Easy to swallow. NOW’s SAMe works well. Repeat customer :)

## Frequently Bought Together

- NOW Foods Supplements, SAMe (S-Adenosyl-L-Methionine) 400 mg, Nervous System Support*, 60 Tablets
- NOW Foods Supplements, Methyl Folate 1,000 mcg, Metabolically Active Folate*, Co-Enzyme B Vitamin, 90 Tablets
- NOW Foods Supplements, TMG Betaine (Trimethylglycine) 1,000 mg, Liver Support*, 100 Tablets

---

## Why Shop on Desertcart?

- 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016
- 🌍 **Shop Globally** — Access 737+ million products across 21 categories
- 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price
- 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members)
- 🔒 **Secure Payments** — Trusted payment options with buyer protection
- ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews

**Shop now:** [https://www.desertcart.com.au/products/5935185-now-foods-supplements-same-s-adenosyl-l-methionine-400-mg](https://www.desertcart.com.au/products/5935185-now-foods-supplements-same-s-adenosyl-l-methionine-400-mg)

---

*Product available on Desertcart Australia*
*Store origin: AU*
*Last updated: 2026-02-23*