Everett LaboratoriesPregnitude Reproductive Dietary Supplement - 60 Fertility Support Packets - Can Promote Regular Ovulation, Regular Menstrual Cycles, and Increase Quality of Eggs

Pregnitude: A First-Line Natural Treatment for all Women with PCOSBy Angela Grassi, MS, RDN, LDN for the PCOS Nutrition Center Blog ([...])Don't let the name of this product fool you: Pregnitude is a high-quality myo-inositol (MYO) supplement for all women with PCOS, not just those looking to get pregnant. Before I tell you why, I want to briefly discuss what MYO is and how it can improve PCOS.What is Myo-Inositol?A member of the B vitamins, MYO is believed to improve egg quality and acts as a secondary messenger involved in glucose utilization. It's believed that women with PCOS may have a defect in secondary messengers contributing to insulin resistance.How I explain this to my patients with PCOS is this: when we eat foods, mostly carbohydrates, they get converted into glucose in our blood stream. We need the glucose to enter our cells to be used for energy. When blood glucose levels rise, a signal (imagine a doorbell is rung) is sent from the cell door to the nucleus telling it to open up. However, with PCOS, the doorbell on the cell door may be defective. This means that it takes longer for the cells to open its doors to glucose resulting in higher amounts of insulin needing to be secreted. MYO, as a secondary messenger, acts to repair the doorbell so that the cell doors open in response to glucose, resulting in less insulin needing to be secreted.Health benefits of myo-inositolMYO is one of the most studied of supplements in women with PCOS. In addition to lowering glucose and insulin levels, MYO has been shown to improve lipid and androgen levels, blood pressure and egg quality in women with PCOS. It has also been shown to aid in weight loss. You can read more about these benefits in our previous blog post and fact sheet about MYO. Because of its numerous benefits, MYO should be considered as a first-line approach in the treatment of all women PCOS, not just those looking to get pregnant.About PregnitudeNow let me tell you why I like Pregnitude. Pregnitude is a tasteless white powder that gets dissolved in water. Each dose of pregnitude contains 2 grams of MYO and 200 mcg folic acid and comes in individually sealed packets. This makes it convenient to take on the go which will increase consistent use. Other than MYO and folic acid, there are no more ingredients, artificial colors, gluten, or sugars added. Compared to some other supplements marketed to women with PCOS, Pregnitude is affordable at $39/box (60 packets, at least a one month supply). Pregnitude is distributed by Everette Labs and has been used in Europe for years as INFOLIC.Personally, I was thrilled with the results of taking Pregnitude (at the PCOS Nutrition Center, we don't recommend a product unless we've used it). At my last physical, I discussed taking Pregnitude with my doctor. I had initial blood work done to check my cholesterol and glucose and then took 2 packets of Pregnitude (the recommended dose) each day for 3 months. I didn't alter my diet, exercise or supplement use.During this period, I experienced bouts of low blood sugar. My doctor recommended I decrease my metformin by 500 mg and I never experienced low blood sugar again while taking Pregnitude. Lean women with PCOS or those that don't have severe insulin resistance may not need the full dose of MYO at 4 grams/day. If you are planning on trying Pregnitude, you may want to start out with one packet per day (2 g MYO) for a week to see how you respond.After 3 months, I repeated my blood work and am pleased to share the results with you: my HDL (the "good" cholesterol) went up 5 points and my CRP went down 1 point. I also saw improvements in glucose as measured by HA1C. An unexpected surprise was that my hair was thicker. Not bad for only 3 months! I plan on continuing with Pregnitude and will get blood taken again (Septemeber 2013) to further assess any improvements in my health. I am also assessing data on clients using Pregnitude and will update on both.Side EffectsBesides the possibility of low blood sugar, Pregnitude is well tolerated. High doses of MYO may have additive effects when taken concurrently with selective serotonin reuptake inhibitor (SSRI) and selective serotonin norepinephrine reuptake inhibitor (SNRI) antidepressant medications. You should use caution when combining high doses of MYO with St. John's Wort or other herbal products or medications that may reduce blood sugar (such as metformin, byetta). Taking Pregnitude with food may minimize low blood sugar.Check out my follow up 6 month review of Pregnitude at [...]

UPDATE 2 (2018): We've gone on to have a second baby! Thanks to myo inositol + vitex we conceived in only 4 months this time around. Great stuff!-------UPDATE: I've been waiting to write this update since February! I am happy to report that our little one DID stick. My husband and I welcomed a baby girl in October 2015. She is such a joy! <3 I realize that Pregnitude/myo-inositol is no miracle drug, but it sure was for us. Someone in the comments mentioned an HSG possibly helping, but we did not have this procedure. We were still in the diagnostic phase of fertility testing (ultrasound and blood and saliva testing looking for hormonal issues). One other consideration of which I've become aware in the past 9 months: if you have the MTHFR mutation, make sure you run Pregnitude by your doctor as it has folic acid rather than folate in it. Pure myo-inositol without folic acid is available elsewhere on Amazon :) I do not have MTHFR, and I know evidence of a link between folate/folic acid processing and MTHFR is contentious, at best, but I know several other women who do and raised this issue, so I thought I'd add it to my review in case it can help someone else.------ORIGINAL REVIEW:Let me start out saying that I have never written a product review. I had to make an exception for Pregnitude. I began taking Pregnitude in October 2014. I am not one to experiment randomly with supplements, but I had done some research based on my cycle charts (Hubs and I use NFP both to get pregnant and once upon a time, to avoid pregnancy. We chart basal temperature, and we use a fertility monitor that measures LH and estrogen levels to identify the fertile window). Based on my charts and a discussion with my OB-GYN, we suspected hormonal imbalance that included weak progesterone and possibly weak ovulation. Namely, I ovulated on the later side (average CD 23) and I had dysfunctional uterine bleeding, including spotting for up to 5 days before my period. For unrelated reasons, we could not start fertility testing right away, so I decided to give Pregnitude a try based on the peer reviewed studies showing improved egg quality. My doctor was supportive. As an aside: he had recommended Vitex a few months earlier, so I also had been taking 800mg/day Nature's Way Vitex since May 2013.The product itself: It is a very fine powder, like powdered sugar with half the sweetness of table sugar. I sprinkled the powder into my coffee in the mornings (no sugar added!) along with milk. I stirred it into a glass of water in the evenings. Compared with many supplements and superfoods (::ahem:: maca), this stuff tastes great. Zero complaints.First cycle: Total bust. I had a 42 day anovulatory cycle, but I think this was due to work stress more than Pregnitude. It takes up to 90 days for oocyte (eggy!) formation, so I knew I had to keep going to see the full effects of the product.Second cycle: I ovulated on CD 17! I had great post-ovulation temperatures that were higher than in cycles past. My pre-period spotting was way, way down, and I had *no* spotting during the follicular phase. No BFP, but I was hopeful.Third cycle: We started fertility testing this cycle. That process, as many of you know, can be rather stressful, so I did not expect much out of this cycle. I fully expected to sit this one out and start Clomid or Femara next cycle. Before the cycle began, I called to ask my doctor whether I could continue taking Pregnitude and Vitex while doing the testing. My doctor said yes! I ovulated on day 19 with LOTS of cramping around ovulation, which seemed to indicate a strong ovulation. I also had a fantastic temperature rise post-O, indicating decent progesterone. Lo and behold, at 9 (yes 9!) days past ovulation, I got my BFP!We have been TTC for 14 months. It took me three cycle of Pregnitude and 4 boxes to get pregnant. Pregnitude is a win for me. It clearly improved my luteal phase spotting and likely upped my progesterone. It also appears to have improved ovulation, making it stronger and moving it forward. Hoping this little one sticks!

I felt very compelled to write a review for this product since my results have been so fantastic... and FAST! I'm 33 and was diagnosed with PCOS about 8 years ago. As long as I can remember I haven't had regular periods - maybe between 2 and 6 times per year. They were crampy and miserable and it would last anywhere from 1-7 days. About 2 months ago I started acupuncture for fertility and my provider suggested I start this powder - 2 packets in water per day while taking my daily herbs etc. Well 2 days after starting this I got a healthy period for roughly 5 days and exactly 30 days later I got another. I'm amazed and obviously I can't be sure if I'm regular now or even ovulating at all, but I'm most definitely on the right track! It's expensive but no more than taking birth control pills or whatever harmful medication your MD might prescribe to regulate a cycle! I also take 5000 IU vitamin D3 and recently started on verdant vitex and Menotrol. I'm hooked and just received 3 more boxes!! There's a slightly sweet taste but otherwise you'd never notice it in regular water. Good luck everyone!July 13 2015 UPDATE:So I religiously took this stuff for about 3-4 months and got my period every month between 28-35 days apart. I stopped taking it every day (maybe 2-4 times per week) and stopped taking my herbs in May - and just found out I'm about 8 weeks pregnant! We've only been trying for that long but this stuff is a miracle! I've never been pregnant and have been told by many gynecologists that it wasn't possible without fertility treatments. If you're in the same boat as I was, try this first! Good luck!!!November 2015 UPDATE:I'm 24 weeks pregnant today and I still can't believe it - neither can any of my doctors! I've moved and had 2 other acupuncturists for normal pregnancy sickness, back pain, etc. and none seem surprised when I shared I got pregnant on Pregnitude! Worth every single penny!!!MARCH 2017 UPDATE:My little man turns 1 next week. I've recommended this product to 2 other people and along with losing weight, I'm convinced this is why they are either pregnant or had a baby. I'm serious when I say this stuff is amazing. Give it a couple months along with losing weight and/or eating healthy and I swear it's worth a shot!DEC 2017 UPDATE:We just starting taking this again in order to get pregnant for the second time! We haven’t been very safe so if I’m suddenly pregnant, we know it’s probably because of this stuff!

-Update-It will be a month in a few days since I started taking Pregnitude. The sleepy feeling that I initially had disappeared after about 2 weeks. I started taking this because my periods were still somewhat irregular due to a miscarriage in August. My normal cycles were 32 days, but this month I started at 28 days. I usually spot 4-5 days before my period and I didn’t have any spotting this time around! I also had a very good, strong ovulation this last month. Not pregnant yet of course, but I’m happy with my results so far while taking Pregnitude. It makes me more optimistic as far as getting pregnant! Hopefully my next update will be good news and I will get my big fat positive I’ve been waiting for!Only giving this 4 stars for now because I’m only going on my 4th day of use. I wanted to try this out for two reasons 1. I unfortunately had a miscarriage in August and my periods are STILL not totally back to normal yet. So I wanted to see if this product would help regulate them. 2. Like most everyone else we have been trying to get pregnant again for almost 5 months with no luck yet. It might not seem like a long time compared to some women, but I thought why not give this a try and see what happens! Some of the things I’ve noticed so far while taking this is how sleepy it makes me! I’m hoping my body will gradually adjust over time. Also it makes you pee A LOT. So make sure to stay hydrated! I can definitely tell I’ve lost a little weight just within the 4 days I have taken Pregnitude which is a plus. To me it had a slight taste when I mixed it with just water, so I have been mixing it with 8 oz. of orange juice both morning and night. This has made it more enjoyable to drink for me at least. As soon as the month is up I will write an update on our progress. Hopefully I will be as lucky as a lot of you, but I’m not going to get my hopes up too high yet!

I seen the reviews on this and wanted to give it a try. I have been TTC but cant due to the fact that I don't know what is wrong with my cycle. I havnt had a period in three months and I am hoping that this will help restart my cycle back to normal. I have been to my doctor and they say I have a think uterine lining. We got it fixed but now I am back to where I started and still dont know whats wrong. Will update with results.Update: 1/03/24Been trying this for a month now and after about a week or two, my period came back. Its been a long period tho cause I have not had one in a while so I am hoping this regulates it back to normal! I have been using this in water as well as tea and OJ and do t notice a difference in taste or usability. I am on box two now and very hopeful that this will help.