---
product_id: 276958946
title: "Life Extension Same 400mg (S-Adenosyl-Methionine) - Supplement for Joint & Liver Support - Non-GMO, Gluten-Free, 60 Count"
brand: "life extension"
price: "A$113"
currency: AUD
in_stock: true
reviews_count: 5
category: "Life Extension"
url: https://www.desertcart.com.au/products/276958946-life-extension-same-400mg-s-adenosyl-methionine-supplement-for-joint
store_origin: AU
region: Australia
---

# Non-GMO & gluten-free purity 400mg clinically studied dose Enteric-coated for optimal absorption Life Extension Same 400mg (S-Adenosyl-Methionine) - Supplement for Joint & Liver Support - Non-GMO, Gluten-Free, 60 Count

**Brand:** life extension
**Price:** A$113
**Availability:** ✅ In Stock

## Summary

> 💥 Elevate your wellness game with Life Extension SAMe — because your cells deserve the best!

## Quick Answers

- **What is this?** Life Extension Same 400mg (S-Adenosyl-Methionine) - Supplement for Joint & Liver Support - Non-GMO, Gluten-Free, 60 Count by life extension
- **How much does it cost?** A$113 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.com.au](https://www.desertcart.com.au/products/276958946-life-extension-same-400mg-s-adenosyl-methionine-supplement-for-joint)

## Best For

- life extension enthusiasts

## Why This Product

- Trusted life extension brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Liver Detox Champion:** Enhances liver function and glutathione production for natural detox
- • **Mood & Joint Harmony:** Clinically backed to nurture mood balance and joint comfort daily
- • **Cellular Powerhouse Boost:** Supports hormone regulation & cellular membrane health for lasting vitality
- • **Clean & Conscious Formula:** Non-GMO, gluten-free, vegetarian tablets crafted in the USA
- • **Precision Delivery System:** Enteric-coated tablets protect potency from stomach acid for maximum effect

## Overview

Life Extension Same 400mg delivers a potent, clinically studied dose of S-Adenosyl-Methionine in 60 enteric-coated vegetarian tablets. Designed to support mood, joint comfort, and liver health, this non-GMO, gluten-free supplement helps replenish a vital compound your body produces less of over time. Manufactured in the USA, it ensures purity and optimal absorption for professionals seeking cellular-level wellness.

## Description

SAMe (S-Adenosyl-Methionine) is a popular nutrient formula for mood health, joint health and liver health. This mood support supplement contains 400 mg of clinically studied S-Adenosyl-Methionine in every dose. SAMe benefits many metabolic functions in the body, from mood and joint health to healthy glutathione production. SAMe contains 60 enteric-coated vegetarian tablets, enough for a 20- to 60-day supply. Non-GMO. Manufactured in the USA.

Review: Would not recommend. I’ve been using SAMe for awhile now and it significantly improved my mood. I tried this brand and had stomach pain within a day that went away when I stopped using it. AOR brand works much better.
Review: Excelente producto

## Features

- HEALTHY AT THE CELLULAR LEVEL—SAMe (S-Adenosyl-Methionine) is a compound that occurs naturally in your body. It helps regulate hormones and maintains cellular membrane health. SAMe is a key participant in many of the critical biological functions that keep you healthy. It’s needed to support neurotransmitter signaling and protein function.
- Product Note: Exposure to heat or sunlight may lead to melting/damage of product. Hence customers are expected to be available during the product delivery
- NURTURE YOUR MOOD, JOINTS & LIVER—Research from the U.S. Department of Health and human services shows that our bodies produce less and less SAMe over time. What’s more, this health-promoting nutrient isn’t found in the foods we eat. That’s why incorporating SAMe into your daily routine will help you support a healthy mood, joint comfort and liver function, especially for the long haul.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B07D2KF4TL |
| ASIN  | B07D2KF4TL |
| Additives | S-Adenosyl-Methionine |
| Age Range Description | Adult |
| Allergen Information | Gluten Free |
| Best Sellers Rank | #17,593 in Health ( See Top 100 in Health ) #545 in Multivitamins Nutritional Supplements |
| Brand | Life Extension |
| Customer Reviews | 4.6 4.6 out of 5 stars (734) |
| Customer reviews | 4.6 4.6 out of 5 stars (734) |
| Date First Available | 8 June 2018 |
| Format | Tablet |
| Is Discontinued By Manufacturer  | No |
| Item model number  | 02174 |
| Manufacturer  | Life Extension |
| Product Dimensions  | 5.72 x 5.72 x 12.7 cm; 99.79 g |
| Serving Recommendation | FOR JOINT SUPPORT: Take one (1) tablet three times daily in divided doses, preferably on an empty stomach, or as recommended by a healthcare practitioner. FOR MOOD SUPPORT: Take one (1) tablet four times daily in divided doses, preferably on an empty stomach, or as recommended by a healthcare practitioner. |
| Units | 60 Count |
| Weight | 0.1 Kilograms |

## Product Details

- **Brand:** Life Extension
- **Diet type:** Vegetarian
- **Flavour:** Unflavored
- **Item dimensions L x W x H:** 5.7 x 5.7 x 12.7 centimeters
- **Item form:** Tablet
- **Item weight:** 100 g
- **Primary supplement type:** protein
- **Product benefits:** Helps maintain stable mood
- **Special ingredients:** S-Adenosyl-Methionine
- **Unit count:** 60 Count

## Images

![Life Extension Same 400mg (S-Adenosyl-Methionine) - Supplement for Joint & Liver Support - Non-GMO, Gluten-Free, 60 Count - Image 1](https://m.media-amazon.com/images/I/71BRLIc8G5L.jpg)
![Life Extension Same 400mg (S-Adenosyl-Methionine) - Supplement for Joint & Liver Support - Non-GMO, Gluten-Free, 60 Count - Image 2](https://m.media-amazon.com/images/I/81xSCMKDEwL.jpg)
![Life Extension Same 400mg (S-Adenosyl-Methionine) - Supplement for Joint & Liver Support - Non-GMO, Gluten-Free, 60 Count - Image 3](https://m.media-amazon.com/images/I/81XJl01WsjL.jpg)
![Life Extension Same 400mg (S-Adenosyl-Methionine) - Supplement for Joint & Liver Support - Non-GMO, Gluten-Free, 60 Count - Image 4](https://m.media-amazon.com/images/I/71nO1MHBb8L.jpg)
![Life Extension Same 400mg (S-Adenosyl-Methionine) - Supplement for Joint & Liver Support - Non-GMO, Gluten-Free, 60 Count - Image 5](https://m.media-amazon.com/images/I/71F7Lc1q-8L.jpg)

## Questions & Answers

**Q: What are SAMe supplements good for?**
A: SAMe supplements benefit many critical metabolic functions in the body, help maintain a stable mood and support joint and liver health.

**Q: How does SAMe support healthy joints?**
A: SAMe supplements benefit many critical metabolic functions in the body, help maintain a stable mood and support joint and liver health.

**Q: What do SAMe supplements do for your mood?**
A: Research by the U.S. Department of Health and Human Services found that SAMe helps maintain a stable mood and healthy outlook.

**Q: Can you take SAMe every day?**
A: SAMe is safe to take every day according to the supplement label or the advice of your healthcare provider. These tablets are recommended one to three times daily to support a healthy mood.

**Q: Should I take SAMe at night or morning?**
A: It is suggested that these supplements are taken on an empty stomach or as recommended by a healthcare provider.

## Customer Reviews

### ⭐ Review
*by K***A on 22 November 2019*

Would not recommend. I’ve been using SAMe for awhile now and it significantly improved my mood. I tried this brand and had stomach pain within a day that went away when I stopped using it. AOR brand works much better.

### ⭐⭐⭐⭐⭐ Review
*by M***Z on 26 October 2024*

Excelente producto

### ⭐⭐⭐⭐⭐ Review
*by S***A on 12 November 2025*

The formula S-Adenosyl-Methionine (SAMe) is one of the most versatile and well-researched compounds. It participates in methylation processes that affect the nervous system, liver, and connective tissues. This dual action makes the formula unique: it supports emotional balance, helps restore cartilage, and improves joint flexibility. Each tablet is individually sealed in foil to prevent oxidation and maintain the stability of the active ingredient. This ensures the formula remains effective throughout its entire shelf life. The brand has long established itself as a reliable creator of thoughtfully developed supplements. Every product is marked by consistent quality and attention to detail, and this formula is an excellent example of their high standards. UPDATE - November 30, 2025: After just a week and a half, I noticed such significant changes that when I saw it was on sale, I immediately ordered 11 more boxes! I originally purchased this SAMe supplement only for joint support - my mood was fine, but I discovered it could be even better! I was surprised - not only did my joints feel much better, but my mood improved significantly as well. The dual-action formula truly works! Even starting with one tablet, I felt positive results. You can adjust the dosage based on your needs and how you feel. I take mine early in the morning on an empty stomach for best results. I’ve been using it for about a month now, and the results continue to impress me. The improvement in joint comfort is especially remarkable. If you’re considering this product, I highly recommend it. The results have been wonderful in every way - both for joint support and emotional well-being. Very happy with this purchase!

## Frequently Bought Together

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*Product available on Desertcart Australia*
*Store origin: AU*
*Last updated: 2026-03-15*