---
product_id: 209222416
title: "SkinMedica TNS Advanced+ Serum - Our Premium Facial Skin Care Product, the Secret to Flawless Skin. Age-Defying Face Serum for Women is Proven to Address Wrinkles and Fine Lines for Glowing Skin,1 Oz"
price: "A$654"
currency: AUD
in_stock: false
reviews_count: 11
url: https://www.desertcart.com.au/products/209222416-skinmedica-tns-advanced-serum-our-premium-facial-skin-care-product
store_origin: AU
region: Australia
---

# Age-Defying Hydration Boost Clinically Proven SkinMedica TNS Advanced+ Serum - Our Premium Facial Skin Care Product, the Secret to Flawless Skin. Age-Defying Face Serum for Women is Proven to Address Wrinkles and Fine Lines for Glowing Skin,1 Oz

**Price:** A$654
**Availability:** ❌ Out of Stock

## Summary

> Unlock Your Glow! ✨

## Quick Answers

- **What is this?** SkinMedica TNS Advanced+ Serum - Our Premium Facial Skin Care Product, the Secret to Flawless Skin. Age-Defying Face Serum for Women is Proven to Address Wrinkles and Fine Lines for Glowing Skin,1 Oz
- **How much does it cost?** A$654 with free shipping
- **Is it available?** Currently out of stock
- **Where can I buy it?** [www.desertcart.com.au](https://www.desertcart.com.au/products/209222416-skinmedica-tns-advanced-serum-our-premium-facial-skin-care-product)

## Best For

- Customers looking for quality international products

## Why This Product

- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Quick Absorption:** Lightweight texture absorbs rapidly for instant benefits.
- • **Wrinkle Reduction:** Clinically proven to diminish fine lines and wrinkles.
- • **Premium Ingredients:** Crafted with cutting-edge technology for optimal results.
- • **Transform Your Skin:** Experience a radiant glow with our advanced formula.
- • **Hydration Powerhouse:** Deeply hydrates for a plump, youthful appearance.

## Overview

SkinMedica TNS Advanced+ Serum is a premium facial skincare product designed to combat signs of aging. This 1 oz serum is clinically proven to reduce wrinkles and fine lines while providing deep hydration, leaving your skin looking youthful and radiant.

## Description

desertcart.com: SkinMedica TNS Advanced+ Serum - Our Premium Facial Skin Care Product, the Secret to Flawless Skin. Age-Defying Face Serum for Women is Proven to Address Wrinkles and Fine Lines for Glowing Skin,1 Oz : Beauty & Personal Care

Review: SKINMEDICA - Try it once & you'll be hooked - I used this product years ago and loved it. I recently purchased it again to be a part of my skin care routine. This product has been clinically proven to reduce fine lines and wrinkles. It absorbs quickly, and it's super easy to pump out and apply. It does provide a dewy/glowy look once applied. Your skin is soft and with long term use, you will see a changes in your fine lines and wrinkles. It is a little pricey, but I feel that if it does it's job, it's well worth it.
Review: Pricey, But Worth It If You Know How to Use It - TNS Advanced+ Serum — (Real Pro Insight!) After years working closely in the skincare industry, I can confidently say that SkinMedica’s TNS Advanced+ Serum is one of the very few luxury skincare products that actually delivers — when used correctly. I’ve repurchased it many times because it continues to show results that nothing else quite matches — even though the nearly $300 price tag still makes me flinch every time. ⸻ Performance: This Advanced+ version is a serious upgrade from the original TNS Essential Serum. It improves: • Fine lines and wrinkles (especially around the eyes and mouth) • Skin texture (feels smoother and more resilient) • Firmness and elasticity (subtle lift effect) • Tone and overall radiance (especially after consistent use) The texture is much lighter and absorbs faster than the old TNS Essential Serum, without feeling greasy or sticky. It layers beautifully with other treatments — essential if you have a complex routine like I do. ⸻ Key Ingredients (Deep Dive): • TNS-MR (Growth Factor Blend): Over 450 growth factors and cytokines that help stimulate skin regeneration and repair visible signs of aging. • Renessensce (RSC) Advanced: A blend of botanicals and peptides that support cell renewal and longevity. • Hydrolyzed Silk, Peptides, and Polysaccharides: Smooth and hydrate the skin, giving an instant soft feel while working deeper over time. • Antioxidant-rich extracts: Help combat environmental aggressors and oxidative stress. Potential Concerns to Know: • Contains fragrance — it’s minimal and generally tolerable, but still there. • Silicones (Dimethicone) — present for smoother application but can bother acne-prone skin types. • Human fibroblast conditioned media — effective but not vegan. ⸻ The Price Reality: At almost $300 a bottle, it’s a major investment. You’re not just paying for ingredients — you’re paying for decades of research, patented technologies, and clinical trials that back its claims. That said, there are ways to build a routine around less expensive supporting products so you don’t break the bank (and yes — I’ll be sharing exactly how soon, stay tuned!). ⸻ Best Dupe/Alternative (if you’re not ready for $300): • Neocutis BIO•SERUM Firm Rejuvenating Growth Factor and Peptide Treatment It’s another clinical-grade growth factor formula, highly effective, and often runs $100+ cheaper than TNS Advanced+ while still delivering excellent results over time. ⸻ Important SkinMedica Note: Out of all SkinMedica products, only two stand head and shoulders above the rest in my professional opinion: • TNS Advanced+ Serum • AHA/BHA Exfoliating Cleanser Everything else? It’s either overpriced, over-fragranced, or underwhelming compared to newer technologies you can find elsewhere. ⸻ Final Verdict: • TNS Advanced+ works — for smoothing, firming, and rejuvenating the skin. • Crazy expensive — but it’s legitimately one of the best growth factor serums available. • Not a miracle in a bottle — best results happen when you build it into a strong, layered skincare routine (and yes, I’ll be sharing mine soon). • Great for aging skin, texture concerns, and anyone serious about long-term skin health. I will absolutely continue buying this until something even better comes along. Like and follow me here on desertcart if you want real, tested skin advice — including how to layer smarter, when to splurge, and when to save!

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN  | B07SCJ445R |
| Best Sellers Rank | #71,570 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #1,439 in Facial Serums |
| Customer Reviews | 3.9 3.9 out of 5 stars (923) |
| Item model number  | 96395 |
| Manufacturer  | AmazonUs/SKJU4 |
| Product Dimensions  | 2 x 2 x 7 inches; 4 ounces |
| UPC  | 300236395100 |

## Product Details

- **Scent:** Aloe
- **Skin Type:** All, Combination, Sensitive
- **Special Ingredients:** Next-generation growth factor blend — supports healthy skin functions
- **Use for:** Face

## Images

![SkinMedica TNS Advanced+ Serum - Our Premium Facial Skin Care Product, the Secret to Flawless Skin. Age-Defying Face Serum for Women is Proven to Address Wrinkles and Fine Lines for Glowing Skin,1 Oz - Image 1](https://m.media-amazon.com/images/I/31435pigcUL.jpg)
![SkinMedica TNS Advanced+ Serum - Our Premium Facial Skin Care Product, the Secret to Flawless Skin. Age-Defying Face Serum for Women is Proven to Address Wrinkles and Fine Lines for Glowing Skin,1 Oz - Image 2](https://m.media-amazon.com/images/I/41jpxbIv7tL.jpg)
![SkinMedica TNS Advanced+ Serum - Our Premium Facial Skin Care Product, the Secret to Flawless Skin. Age-Defying Face Serum for Women is Proven to Address Wrinkles and Fine Lines for Glowing Skin,1 Oz - Image 3](https://m.media-amazon.com/images/I/41mgmrKPy1L.jpg)
![SkinMedica TNS Advanced+ Serum - Our Premium Facial Skin Care Product, the Secret to Flawless Skin. Age-Defying Face Serum for Women is Proven to Address Wrinkles and Fine Lines for Glowing Skin,1 Oz - Image 4](https://m.media-amazon.com/images/I/41nJnq0oCbL.jpg)
![SkinMedica TNS Advanced+ Serum - Our Premium Facial Skin Care Product, the Secret to Flawless Skin. Age-Defying Face Serum for Women is Proven to Address Wrinkles and Fine Lines for Glowing Skin,1 Oz - Image 5](https://m.media-amazon.com/images/I/41tCMmQp2QL.jpg)

## Questions & Answers

**Q: How long does it last?**
A: I assume you are asking how long does the 1 ounce bottle of TNS Advanced+ Serum last. My wife uses the product twice daily on her face, neck, and upper chest. She says she uses two pumps twice daily, so four pumps per day, and the 1 ounce bottle will last about two months.

**Q: How do I know if this product is legit and not expired or counterfeit**
A: You don’t. Not from Amazon. I had to send it back (pump didn’t work), and 2 weeks later Amazon still hasn’t refunded my money or replaced it. The product is good, just don’t buy it from here.

**Q: What happened to the red serum?**
A: New formula.  Gray container replaced with white container and contents changed too.  Now the product inside has a clear stream and a white stream that you combine in your palm before you put it on your face.

**Q: How does this compare to SkinMedica TNS Essential Serum?**
A: It’s the same.

## Customer Reviews

### ⭐⭐⭐⭐⭐ SKINMEDICA - Try it once & you'll be hooked
*by D***L on August 8, 2025*

I used this product years ago and loved it. I recently purchased it again to be a part of my skin care routine. This product has been clinically proven to reduce fine lines and wrinkles. It absorbs quickly, and it's super easy to pump out and apply. It does provide a dewy/glowy look once applied. Your skin is soft and with long term use, you will see a changes in your fine lines and wrinkles. It is a little pricey, but I feel that if it does it's job, it's well worth it.

### ⭐⭐⭐⭐⭐ Pricey, But Worth It If You Know How to Use It
*by V***R on April 29, 2025*

TNS Advanced+ Serum — (Real Pro Insight!) After years working closely in the skincare industry, I can confidently say that SkinMedica’s TNS Advanced+ Serum is one of the very few luxury skincare products that actually delivers — when used correctly. I’ve repurchased it many times because it continues to show results that nothing else quite matches — even though the nearly $300 price tag still makes me flinch every time. ⸻ Performance: This Advanced+ version is a serious upgrade from the original TNS Essential Serum. It improves: • Fine lines and wrinkles (especially around the eyes and mouth) • Skin texture (feels smoother and more resilient) • Firmness and elasticity (subtle lift effect) • Tone and overall radiance (especially after consistent use) The texture is much lighter and absorbs faster than the old TNS Essential Serum, without feeling greasy or sticky. It layers beautifully with other treatments — essential if you have a complex routine like I do. ⸻ Key Ingredients (Deep Dive): • TNS-MR (Growth Factor Blend): Over 450 growth factors and cytokines that help stimulate skin regeneration and repair visible signs of aging. • Renessensce (RSC) Advanced: A blend of botanicals and peptides that support cell renewal and longevity. • Hydrolyzed Silk, Peptides, and Polysaccharides: Smooth and hydrate the skin, giving an instant soft feel while working deeper over time. • Antioxidant-rich extracts: Help combat environmental aggressors and oxidative stress. Potential Concerns to Know: • Contains fragrance — it’s minimal and generally tolerable, but still there. • Silicones (Dimethicone) — present for smoother application but can bother acne-prone skin types. • Human fibroblast conditioned media — effective but not vegan. ⸻ The Price Reality: At almost $300 a bottle, it’s a major investment. You’re not just paying for ingredients — you’re paying for decades of research, patented technologies, and clinical trials that back its claims. That said, there are ways to build a routine around less expensive supporting products so you don’t break the bank (and yes — I’ll be sharing exactly how soon, stay tuned!). ⸻ Best Dupe/Alternative (if you’re not ready for $300): • Neocutis BIO•SERUM Firm Rejuvenating Growth Factor and Peptide Treatment It’s another clinical-grade growth factor formula, highly effective, and often runs $100+ cheaper than TNS Advanced+ while still delivering excellent results over time. ⸻ Important SkinMedica Note: Out of all SkinMedica products, only two stand head and shoulders above the rest in my professional opinion: • TNS Advanced+ Serum • AHA/BHA Exfoliating Cleanser Everything else? It’s either overpriced, over-fragranced, or underwhelming compared to newer technologies you can find elsewhere. ⸻ Final Verdict: • TNS Advanced+ works — for smoothing, firming, and rejuvenating the skin. • Crazy expensive — but it’s legitimately one of the best growth factor serums available. • Not a miracle in a bottle — best results happen when you build it into a strong, layered skincare routine (and yes, I’ll be sharing mine soon). • Great for aging skin, texture concerns, and anyone serious about long-term skin health. I will absolutely continue buying this until something even better comes along. Like and follow me here on Amazon if you want real, tested skin advice — including how to layer smarter, when to splurge, and when to save!

### ⭐ BE AWARE OF SUBSCRIBE AND SAVE HENCE 1 STAR - PRODUCT IS A 5 STAR
*by D***R on November 26, 2024*

Be aware of subsribe and save for this product. I have subscribe and save for this since it cost alot and it was cheaper that way. I did not need my back up one until today. When I opened it, it would not expel the cream in the right pump. Only the left side of the pump worked. I tried to exchange it, but the last date to return it was in October. I called customer service since Amazon has always been so wonderful to help with problems. However, this time they would not help. It is past the return window, even though it is broken! So my advice to you is it is a wonderful product although it is pricey, I will not buy another for awhile (because of the cost). If you have subscribe and save for this product, my whole reason for this review is to tell you when you receive your bottle check it right away! I wish I had. The only problem with that is now it won't be fresh if you don't need it for awhile. Since this has happened to my pump, I have checked into this product and it looks as though this has been a problem for some with only one side of the pump working. All the more reason to check it works when you receive it.

## Frequently Bought Together

- SkinMedica TNS Advanced+ Serum - Our Premium Facial Skin Care Product, the Secret to Flawless Skin. Age-Defying Face Serum for Women is Proven to Address Wrinkles and Fine Lines for Glowing Skin,1 Oz
- SkinMedica AHA/BHA Exfoliating Face Wash - Gentle Facial Exfoliating Scrub with Jojoba Oil for Smoother, Radiant Skin - Helps Improve the Appearance of Skin Tone & Texture (6 Fl Oz)
- SkinMedica Rejuvenative Moisturizer - Daily Face Lotion for Women, Oil-Free Facial Cream and Moisturizer Ideal for Normal and Dry Skin, 2 Oz

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*Product available on Desertcart Australia*
*Store origin: AU*
*Last updated: 2026-03-19*