---
product_id: 15078466
title: "II Large Dog, 4 pack"
brand: "advantage"
price: "A$119"
currency: AUD
in_stock: true
reviews_count: 8
category: "Advantage"
url: https://www.desertcart.com.au/products/15078466-ii-large-dog-4-pack
store_origin: AU
region: Australia
---

# Waterproof after 24 hours Kills fleas in 12 hours 30-day continuous protection II Large Dog, 4 pack

**Brand:** advantage
**Price:** A$119
**Availability:** ✅ In Stock

## Summary

> 🐾 Stay ahead of fleas—because your dog deserves the best defense!

## Quick Answers

- **What is this?** II Large Dog, 4 pack by advantage
- **How much does it cost?** A$119 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.com.au](https://www.desertcart.com.au/products/15078466-ii-large-dog-4-pack)

## Best For

- advantage enthusiasts

## Why This Product

- Trusted advantage brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Month-Long Defense:** Breaks the flea life cycle with 30 days of uninterrupted protection.
- • **Perfect for Large Dogs:** Specifically formulated for dogs 21-55 lbs, ensuring optimal effectiveness.
- • **Rapid Flea Elimination:** Starts killing fleas within 12 hours—no waiting, no itching.
- • **Waterproof & Fragrance-Free:** Keeps working rain or shine, with no overpowering scents.
- • **Vet-Recommended & Hassle-Free:** Trusted by vets, easy topical application—no prescription needed.

## Overview

Advantage II Large Dog is a vet-recommended, topical flea treatment designed for dogs weighing 21 to 55 lbs. It kills adult fleas, larvae, and eggs within 12 hours and provides 30 days of waterproof, fragrance-free protection. Easy to apply and available over the counter, it breaks the flea life cycle to keep your dog comfortable and flea-free all month long.

## Description

Product Description Advantage II Large Dog is the vet-recommended prevention and treatment of flea and lice infestations in dogs. Advantage II Large Dog flea treatment and prevention kills adult fleas, flea larvae and flea eggs to deliver total flea protection to your dog or puppy. In fact, within 12 hours of application, Advantage II Large Dog topical treatment gets straight to work killing fleas through contact, so they don’t have to bite your dog to die.This 30-day treatment effectively breaks the flea life cycle, controlling existing flea and lice infestations and preventing further infestations all month long. Fleas not only cause discomfort; they can also pose other health risks. Monthly use of Advantage II Large Dog is important to protect your dog against fleas that may cause transmission of tapeworms in dogs, Flea Allergy Dermatitis and flea bite anemia.That’s why Advantage II topical, spot-on formula makes application simple - going on in seconds. It's easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that Advantage II is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects. Advantage II Large Dog flea and lice protection is effective on both indoor and outdoor dogs. Your dog should be at least 7 weeks old and weigh 21 to 55 lbs. to use Advantage II Large Dog.For the ultimate convenience in care, Advantage II Large Dog is available over the counter – no prescription needed. And, you can stock up with a subscription for regular doorstep deliveries so you never miss a monthly treatment. Once Advantage II Large Dog is applied, your dog is ready to get right back to exploring his favorite places – from the backyard to the dog park.Advantage II Large Dog is a trademark of Elanco or its affiliates. Brand Story By Advantage

Review: A Helpful Tool In Our Flea Control Regimen! - We have double coated, long haired, very furry large Northern Breed Mixed Dogs. Unfortunately, fleas are a year round problem here in the San Francisco Bay Area where we live ... Ugh! Advantage II Topical Flea Treatment & Prevention is an effective tool in our flea control regimen. - Easy to apply the topical drops on your dog's skin along the backbone. - Our dogs have never had any skin irritation or other negative reactions with this product. - The 6 pack is a terrific value. I highly recommend this product.
Review: Seresto Flea collars are life changing for pets and owner💯 - Life Changing Flea Collars that really do last 8 months. No more battling fleas! Retired Rescue and breeder of 30 years. Seresto Flea collars are the only way and no fleas or ticks ever again.

## Features

- Vet recommended flea treatment and prevention for dogs at weighing 21 to 55 lbs., at least 7 weeks of age
- Kills adult fleas, flea larvae and flea eggs for total flea prevention and treatment
- Same-day effectiveness, kills fleas within 12 hours of application and keeps working for 30 days
- Easy-to-apply topical treatment, no prescription needed
- Fragrance-free formula, waterproof after 24 hours

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B004QRFJA4 |
| ASIN  | B004QRFJA4 |
| Age Range Description | 7 weeks and older |
| Best Sellers Rank | #2,296 in Pet Supplies ( See Top 100 in Pet Supplies ) #13 in Dog Flea Drops |
| Brand Name | Advantage |
| Breed Recommendation | Large |
| Care Instructions | Topical Treatment |
| Color | Blacks & Grays |
| Country of Origin | Germany |
| Customer Reviews | 4.5 4.5 out of 5 stars (19,012) |
| Date First Available | March 5, 2011 |
| Date First Available  | March 5, 2011 |
| Department | Flea & Tick |
| Department  | Flea & Tick |
| Directions | Application Instructions: 1. Use only on dogs. 2. Hold applicator tube in an upright position. Pull cap off tube. 3. Turn the cap around and place other end of cap back on tube. Twist cap to break seal, then remove cap from tube. 4. Apply the entire contents of the tube evenly to three or four spots on the top of the back from the shoulder to the base of the tail. At each spot, part the hair until… |
| Is Discontinued By Manufacturer  | No |
| Item Dimensions LxWxH | 6.5 x 1 x 4.25 inches |
| Item Package Dimensions L x W x H | 4.92 x 4.49 x 1.42 inches |
| Item Weight | 1.6 ounces |
| Item model number | 86336707 |
| Item model number  | 86336707 |
| Manufacturer | Elanco US Inc |
| Manufacturer  | Elanco US Inc |
| Manufacturer recommended age  | 1 month and up |
| Model Name | Advantage II |
| Number of Items | 4 |
| Product Dimensions  | 6.5 x 1 x 4.25 inches; 1.6 ounces |
| Size | 4-Pack |
| Specific Uses for Product | Parasites |
| Style | Large Dog |
| Target Audience Keyword | Dogs |

## Product Details

- **Active Ingredients:** Imidacloprid, Pyriproxyfen
- **Age Range (Description):** 7 weeks and older
- **Allergen Information:** Allergen-Free
- **Brand:** Advantage
- **Dog Breed Size:** Large
- **Item Form:** Topical
- **Item Volume:** 10 Milliliters
- **Item Weight:** 1.6 ounces
- **Scent:** Unscented
- **UPC:** 724089202833

## Images

![II Large Dog, 4 pack - Image 1](https://m.media-amazon.com/images/I/71cacwZn0PL.jpg)

## Available Options

This product comes in different **Size, Style** options.

## Questions & Answers

**Q: Is there a warning to keep the dog away from cats for 24 hours after treatment with Advantage, as is found on Frontline?**
A: Yes, there is a seperate and specific warning about not using it on cats and keeping dogs away from cats for 24 hrs. Highlited in yellow.

**Q: Is it ok to put advantix and advantage ii simultaneously on a larger dog? advantix for l and advantage ii for sm.  that amount needed for bigger dog.**
A: Each box will have a different expiration date on it. We had a box for at least a year, it still worked on the dog.

**Q: What are ingredients?**
A: Strange that they leave this part out of the description as it is rather important. I have used this product on several dogs for years and purchased here and the online pet pharmacy out of Canada (wife ordered and I forget the name) but never had a problem but just like humans, some dogs have different reactions than others to certain products/chemicals, so do be careful to follow directions and monitor a bit to make sure your pet is taking it as expected and not having any reactions.  Since they don't list it, I would email them seller directly, and/or look on the manufacturer website for more info.

**Q: what is the difference between Advantage 11 and Advantage?**
A: Advantage II Is a better flea control and does not wash off as does Advantage.  Advantage II is what you want!

## Customer Reviews

### ⭐⭐⭐⭐⭐ A Helpful Tool In Our Flea Control Regimen!
*by M***S on January 3, 2026*

We have double coated, long haired, very furry large Northern Breed Mixed Dogs. Unfortunately, fleas are a year round problem here in the San Francisco Bay Area where we live ... Ugh! Advantage II Topical Flea Treatment & Prevention is an effective tool in our flea control regimen. - Easy to apply the topical drops on your dog's skin along the backbone. - Our dogs have never had any skin irritation or other negative reactions with this product. - The 6 pack is a terrific value. I highly recommend this product.

### ⭐⭐⭐⭐⭐ Seresto Flea collars are life changing for pets and owner💯
*by S***Y on February 20, 2026*

Life Changing Flea Collars that really do last 8 months. No more battling fleas! Retired Rescue and breeder of 30 years. Seresto Flea collars are the only way and no fleas or ticks ever again.

### ⭐⭐⭐⭐⭐ Gets the job done
*by D***Y on August 1, 2017*

It's hard to find an affordable, OTC flea repellant that applies monthly on the neck and WORKS. This stuff does the job. I have two 25 pound dogs and the small dog application is way smaller and ridiculously expensive. Our monthly budget is super tight, but I must take care of my animals, so I went looking for a cheaper way to get a good OTC flea repellant that works. This WORKS. For me. I can't guarantee it'll work for you, of course. I don't know you, I don't know your dog. Duh. Fleas are different all over the nation and some have developed immunity to this kind of repellant and some repellants just don't work. Disclaimer: I'm about to tell you what I do with this. If you decide to do the same, I take no responsibility for your results. I'm just saying this works for me. Ok, so I did some research on The Innernetz. I found out that if you get the extra large dog size, you get way more medicine for your money. It makes it cost way less per ml. I got this item. I got a little, airtight, really secure glass bottle, and a 1.0ml syringe. All from Amazon. The research I found said to use 1.2ml for a 25 pound dog. So at the beginning of every month, I open one extra large dog application, squirt it into the little glass jar, stick in the blunt syringe, and pull the plunger all the way, which is about 1.2ml. I then apply it on my dogs just as I would the small dog application. No fleas in our house. Thank GOD. Because once they get in, they're almost impossible to get rid of, and it's crazy-making. BTW, dusting diatomaceous earth and using an insect growth regulator are a good way to get rid of an infestation.

## Frequently Bought Together

- Advantage II Large Dog Vet-Recommended Flea Treatment & Prevention | Dogs 21-55 lbs. | 4-Month Supply
- Advantage II Large Cat Vet-Recommended Flea Treatment & Prevention | Cats Over 9 lbs. | 6-Month Supply
- Advantage II Medium Dog Vet-Recommended Flea Treatment & Prevention | Dogs 11-20 lbs. | 4-Month Supply

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*Product available on Desertcart Australia*
*Store origin: AU*
*Last updated: 2026-03-14*